邮箱：liuyliwd@vip.sina.com
个人简介
2004/08-2016/10 北京中医药大学中药学院助教、讲师、副研究员
2016/11-至今 尊龙凯时人生就是博首页副研究员、研究员
2018/03-2019/03 美国匹兹堡大学医学院，访问学者
研究方向
1）药用植物功能基因与合成生物学研究
2）中药“分子身份证”研究
3）中药抗糖尿病活性成分的筛选及分子机制研究
主要成果
以第一作者及通讯作者发表SCI论文20余篇，核心期刊论文50余篇。代表作如下：
[1] Licochalcone A alleviates abnormal glucolipid metabolism and restores energy homeostasis in diet-induced diabetic mice, Phytotherapy Research, 2024, 38(1): 196-213. DOI: 10.1002/ptr.8044
[2] The role of autophagy in insulin resistance and glucolipid metabolism and potential use of autophagy modulating natural products in the treatment of type 2 diabetes mellitus, Diabetes/Metabolism Research and Reviews, 2024, 40(1): e3762. DOI: 10.1002/dmrr.3762
[3] The potential of therapeutic strategies targeting mitochondrial biogenesis for the treatment of insulin resistance and type 2 diabetes mellitus, Archives of Pharmacal Research, 2024, 47(3): 219-248. DOI: 10.1007/s12272-024-01490-5
[4] Isoliquiritigenin, a potential therapeutic agent for treatment of inflammation-associated diseases, Journal of Ethnopharmacology, 2024, 318(Pt B): 117059. DOI: 10.1016/j.jep.2023.117059
[5] COMT, CRTZ, and F3'H regulate glycyrrhizic acid biosynthesis in Glycyrrhiza uralensis hairy roots, Plant Growth Regulation, 2023, 101(1): 115-130. DOI: 10.1007/s10725-023-01005-0
[6] Isoliquiritigenin alleviates diabetic symptoms via activating AMPK and inhibiting mTORC1 signaling in diet-induced diabetic mice, Phytomedicine, 2022, 98: 153950. DOI: 10.1016/j.phymed.2022.153950
[7] ARPI, β-AS, and UGE regulate glycyrrhizin biosynthesis in Glycyrrhiza uralensis hairy roots, Plant Cell Reports, 2021, 40 (7): 1285-1296. DOI: 10.1007/s00299-021-02712-6
[8] Molecular mechanisms underlying the anticancer activities of licorice flavonoids, Journal of Ethnopharmacology, 2021, 267: 113635. DOI: 10.1016/j.jep.2020.113635
[9] The anti-diabetic activity of licorice, a widely used Chinese herb, Journal of Ethnopharmacology, 2020, 263: 113216. DOI: 10.1016/j.jep.2020.113216
[10] Identification of biosynthetic pathways involved in flavonoid production in licorice by RNA-seq based transcriptome analysis, Plant growth regulation, 2020, 92 (1): 15-28. DOI: 10.1007/s10725-020-00616-1
主持国家自然科学基金1项、北京市青年英才计划1项、国家工业和信息化部中药材扶持项目1项、北京中医药大学杰出青年人才项目1项、中央高校基本科研项目1项。
指导大学生创新课题1项，研究生课题2项。共指导研究生11届，21人，其中4人获得国家奖学金，19人获得学业一等奖学金，已毕业8届，16人。