邮箱:nali@bucm.edu.cn
个人简介
李娜,女,尊龙凯时人生就是博首页免疫与微生物学教研室,副研究员,硕士生导师。中国中医药信息学会产学研融合发展分会理事,世界中医药学会联合会过敏性疾病专业委员会理事,北京中医药学会中医基础工作委员会青年委员。曾获北京市优秀博士论文、中国农业大学十篇优秀博士论文、北京市优秀研究生毕业生等奖项。参编教材3部,主讲本科生课程3门。
研究方向
基于微生物多组学技术研究肠道菌群代谢及中医药的调节作用。
主要成果
l 主持/参与课题
主持国家自然科学基金青年项目、北京市自然科学基金面上项目、中华中医药学会青年人才托举工程项目等课题5项,参与国家自然科学基金面上项目、北京市自然科学基金重点项目等8项。
l 发表论文(#第一作者,*通讯作者)
以第一/通讯作者在Microbiome(IF13.8)、Gut Microbes(IF12.2)等国内外知名期刊上发表论文12篇,参与发表论文19篇。
代表性论文
1. Li N#, Zhang C#, Cui J, Wang Q, Li T*, Peng G*. The classroom teaching of Medical Immunology based on Nobel Prize cases improves the critical thinking skills of undergraduate students in the medical university. BMC Medical Education, 2024, 24:1213 (co-first author, 2023IF=2.7, JCR Q1)
2. Li N#, Ma P#, Li Y#, Shang X, Nan X, Shi L, Han X, Liu J, Hong Y, Li Q, Cui J, Li J*, Peng G*. Gut microbiota-derived 12-ketolithocholic acid suppresses the IL-17A secretion from colonic group 3 innate lymphoid cells to prevent the acute exacerbation of ulcerative colitis. Gut Microbes, 2023, 15(2): 2290315 (co-first author, 2023IF=12.2, 中科院1区Top, JCR Q1)
3. Li Y#, Li N#, Liu J, Wang T, Dong R, Ge D, Peng G*. Gegen Qinlian Decoction alleviates experimental colitis and concurrent lung inflammation by inhibiting the recruitment of inflammatory myeloid cells and restoring microbial balance. Journal of Inflammation Research, 2022, 15:1273-1291 (co-first author, 2023IF=4.2, JCR Q2)
4. Wang Y#, Li N#, Li Q, Liu Z, Li Y, Kong J, DongR, Ge D, Li J*, Peng G*. Xuanbai Chengqi decoction ameliorates pulmonary inflammation via reshaping the gut microbiota and rectifying the Th17/Treg imbalance in a murine model of chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Disease, 2021, 16:3317-3335 (co-first author, 2023IF=2.7, JCR Q2)
5. Li N#, Zuo B, Huang S, Zeng B, Han D, Li T, Liu T, Wu Z, Wei H*, Zhao J*, Wang J*. Spatial heterogeneity of bacterial colonization across different gut segments following inter-species microbiota transplantation. Microbiome, 2020, 8:161 (first author, 2023IF=13.8, 中科院1区Top, JCR Q1)
6. Li N#, Huang S, Jiang L, Dai Z, Li T, Han D, Wang J*. Characterization of the early-life microbiota development and predominant Lactobacillus species at distinct gut segments of low- and normal-birth-weight piglets. Frontiers in Microbiology, 2019, 10:797 (first author, 2023IF=4.0, ESI高被引论文, JCR Q2)
7. Li N#, Huang S, Jiang L, Wang W, Li T, Zuo B, Li Z, Wang J*. Differences in the gut microbiota establishment and metabolome characteristics between low and normal-birth-weight piglets during early-life. Frontiers in Microbiology, 2018, 9:1798 (first author, 2023IF=4.0, JCR Q2)
8. Li N#, Wang W, Wu G, Wang J*. Nutritional support for low birth weight infants: Insights from animal studies. British Journal of Nutrition, 2017, 117(10):1390-1402 (first author, 2023IF=3.0, JCR Q2)
9. 张崇豪, 马沛广, 刘华琛, 苏佳龙, 刘洁, 李亚兰, 徐贵川, 李娜*, 彭桂英*. 基于菌群人源化模型探究乌梅丸加减对湿热瘀阻证溃疡性结肠炎Th17/Treg平衡及肠道菌群的调节作用. 中国实验方剂学杂志. 2025, 31(20). Doi: 10.13422/j.cnki.syfjx.20242337 (共同通讯, 中文核心期刊)
l 发明专利
李娜, 彭桂英, 李亚兰, 商学凯, 洪雁飞. 12-酮基石胆酸在制备防治溃疡性结肠炎的药物中的应用, 2024-04-05, 中国,ZL202310736796.6
l 主讲课程
《微生物与免疫学》、《生命科学基础概论》、《医学免疫学与微生物学》