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陈建波

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邮箱:chenjianbo@bucm.edu.cn

个人简介

陈建波,尊龙凯时人生就是博生物制药系副研究员,硕士生导师。在清华大学化学系先后获得本科、硕士、博士学位,完成博士后工作。主要研究领域为中药冻干赋形制剂、中药炮制与质量评价、中医药分子光谱学。已经以第一作者或通讯作者发表SCI论文30余篇,出版中英文学术著作3部,主持国家自然科学基金、北京市自然科学基金等多项课题。

研究方向

(1)中药冻干赋形制剂工艺原理与产品研发

(2)中药细胞外囊泡的基础研究与制剂技术

(3)鲜药与发酵饮片的炮制机理与质量评价

(4)中医药复杂体系的分子光谱理论和方法

主要成果

代表论文:

[1]   L. Zhong, J. Sun, S. Li, Y. Qi, M. Luo, L. Dong*, J. Chen*, Scorch processing of rhubarb (Rheum tanguticum Maxim. ex Balf.) pyrolyzed anthraquinone glucosides into aglycones and improved the therapeutic effects on thromboinflammation via regulating the complement and coagulation cascades pathway, Journal of Ethnopharmacology, 333 (2024) 118475.

[2]   J. Sun, L. Zhong, L. Dong*, J. Chen*, Mid-infrared spectroscopic identification of the right-baked rhubarb for ulcerative colitis therapy, Spectrochimica Acta Part A, 314 (2024) 124244.

[3]   J. Sun, B. Zhu, Y. Sun, Z. Li, L. Dong*, J. Chen*, Fourier transform infrared spectroscopic markers of the scorching degree of Scutellariae Radix related to the variation patterns of flavonoids and carbohydrates, Spectrochimica Acta Part A, 290 (2023) 122312.

[4]   L. Zhong, M. Xu, S. Sun, Q. Zhou, L. Dong*, J. Chen*, Attenuated total reflection Fourier transform infrared mapping for the identification of the prescribed and abnormal ingredients of herbal powder preparations, Applied Spectroscopy, 77 (2023) 774-785.

[5]   L. Yang, L. Yang, W. Pei, L. Dong, J. Chen*, Color-reflected chemical regulations of the scorched rhubarb (Rhei Radix et Rhizoma) revealed by the integration analysis of visible spectrophotometry, Fourier transform infrared spectroscopy and high performance liquid chromatography, Food Chemistry, 367 (2022) 130730.

[6]   L. Yang, T. Li, L. Yang, L. Dong*, J. Chen*, Two-dimensional correlation spectroscopy indicates the infrared spectral markers of the optimum scorching degree of rhubarb (Rhei Radix et Rhizoma) to enhance the anti-inflammatory activity, Spectrochimica Acta Part A, 270 (2022) 120853.

[7]   Y. He, M. Xu, L. Dong*, J. Chen*, Infrared spectroscopic identification of mineral drugs in herbal preparations with thermogravimetry-guided thermal separation - A case study of alum in a herbal powder for oral ulcer, Journal of Molecular Structure, 1249 (2022) 131581.

[8]   J. Chen, J. Fan, D. Wang, S. Yue, X. Zhai, Y. Gong, J. Wang*, Rapid and intelligent discrimination of Notopterygium incisum and Notopterygium franchetii by infrared spectroscopic fingerprints and electronic olfactory fingerprints, Spectrochimica Acta Part A, 232 (2020) 118176.

[9]   L. Yang, L. Yang, S. Sun, Q. Zhou, L. Dong*, J. Chen*, Cascading chemical transitions of rhubarb (Rhei Radix et Rhizoma) during the scorching process revealed by heated ATR-FTIR spectroscopy and two-dimensional correlation analysis, Journal of Molecular Structure, 1216 (2020) 128307.

[10]  Y. Liu, W. Pei, S. Sun, Q. Zhou, J. Wang*, J. Chen*, Protein-sugar interaction between Asini Corii Colla (donkey-hide gelatin) and Lycii Fructus (goji berry) evaluated by temperature-resolved ATR-FTIR and moving-window two-dimensional correlation spectroscopy, Journal of Molecular Structure, 1211 (2020) 128072.

学术著作:

[1]   孙素琴, 周群, 陈建波. 红外光谱分析技术. 北京: 中国质检出版社/中国标准出版社, 2013.

[2]   Sun Su-qin, Zhou Qun, Chen Jian-bo. Infrared Spectroscopy for Complex Mixtures - Applications in Food and Traditional Chinese Medicine. Beijing: Chemical Industry Press, 2011.

[3]   孙素琴, 周群, 陈建波. 中药红外光谱分析与鉴定. 北京: 化学工业出版社, 2010.