邮箱:xuanlong@bucm.edu.cn;hgr@bucm.edu.cn
个人简介
1994.7~1996.7 美国加州圣迭戈联合制药公司,研究员
1996.7~2000.3 中山大学,生物化学系主任、教授
2000.2~2008.12 中山大学,尊龙凯时人生就是博院长、教授
2008.3~2013.1 中山大学,副校长、教授
2013.1~至今 北京中医药大学,校长、教授
研究方向
徐安龙教授团队长期从事免疫学与中医药免疫调节机制研究,主要研究方向如下:
(1)免疫性疾病的发病机制研究;
(2)中医药防治免疫性疾病的疗效机理研究;
(3)中药配伍“减毒增效”的科学内涵研究。
主要成果
作为通讯作者在Nature, Cell、Nat Cell Biol、Gut、J Hepatol、Kidney Int、Nat Commun、Natl Sci Rev、Autoimmun Rev、Signal Transduct Target Ther、Am J Hum Genet、Genome Res、PNAS、Cell Res、Sci Signal等国际学术刊物发表SCI 收录论文200余篇。先后主持国家杰出青年基金、973项目、863项目、国家自然科学基金重点项目、国家重点研发计划等国家级科研项目17项。
代表性论文如下:
(1) Discovery of an active RAG transposon illuminates the origins of V(D)J recombination. Cell. 2016 Jun 30; 166(1):102-14. (IF: 30.41)
(2) Transposon molecular domestication and the evolution of the RAG recombinase. Nature. 2019 May;569(7754):79-84. (IF: 42.779)
(3) Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS. Nat Cell Biol.2019 Nov;21(11):1346-1356. (IF: 20.042)
(4) Generation of hepatobiliary organoids from human induced pluripotent stem cells. J Hepatol. 2019 Jun;70(6):1145-1158. (IF: 20.582)
(5) RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer. Gut. 2021 Sep;70(9):1698-1712. (IF: 31.793)
(6) Course monitoring of membranous nephropathy: Both autoantibodies and podocytes require multidimensional attention. Autoimmun Rev. 2022 Feb;21(2):102976.
(7) Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB. Signal Transduct Target Ther. 2022 Jul 29;7(1):253. (IF: 38.104)
(8) Single cell landscape of parietal epithelial cells in healthy and diseased states. Kidney Int. 2023(accepted)(IF: 18.998)